3HOV

Complete RNA polymerase II elongation complex II

3HOV の概要

• エントリーDOI: 10.2210/pdb3hov/pdb
• 関連するPDBエントリー: 3HOU 3HOW 3HOX 3HOY 3HOZ
• 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11, ... (17 entities in total)
• 機能のキーワード: rna polymerase ii, metal-binding, transcription bubble, elongation complex, transcription, dna-rna mismatch, dna-binding, dna-directed rna polymerase, isopeptide bond, magnesium, nucleotidyltransferase, nucleus, phosphoprotein, transferase, ubl conjugation, zinc, zinc-finger, polymorphism, cytoplasm, dna damage, dna repair, mrna processing, transferase-dna-rna hybrid complex, transferase-dna-rna complex, transferase/dna/rna
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast); 詳細
• 細胞内の位置: Nucleus: P04050 P38902 P08518 P16370 P20433 P20434 P34087 P20436 P27999; Nucleus, nucleolus: P22139 P40422; Cytoplasm: P20435
• タンパク質・核酸の鎖数: 15
• 化学式量合計: 532108.68

構造登録者

Sydow, J.F.,Brueckner, F.,Cheung, A.C.M.,Damsma, G.E.,Dengl, S.,Lehmann, E.,Vassylyev, D.,Cramer, P. (登録日: 2009-06-03, 公開日: 2009-07-28, 最終更新日: 2023-11-01)

• 主引用文献: Sydow, J.F.,Brueckner, F.,Cheung, A.C.M.,Damsma, G.E.,Dengl, S.,Lehmann, E.,Vassylyev, D.,Cramer, P.; Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.; Mol.Cell, 34:710-721, 2009; PubMed: 19560423; DOI: 10.1016/j.molcel.2009.06.002

実験手法

X-RAY DIFFRACTION (3.5 Å)