3HMS

Crystal Crystal structure of the N-terminal fragment (28-126) of the human hepatocyte growth factor/scatter factor, orthorhombic crystal form

Summary for 3HMS

Entry DOI	10.2210/pdb3hms/pdb
Related	1BHT 1GMN 1GMO 1GP9 1NK1 2HGF 2QJ2 2QJ4 3HMR 3HMT 3HN4
Descriptor	Hepatocyte growth factor, SULFATE ION (3 entities in total)
Functional Keywords	hgf/sf, hormone/growth factor, disulfide bond, glycoprotein, growth factor, kringle, pyrrolidone carboxylic acid, serine protease homolog, hormone
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	11890.74
Authors	Tolbert, W.D. (deposition date: 2009-05-29, release date: 2010-06-09, Last modification date: 2023-09-06)
Primary citation	Tolbert, W.D.,Daugherty-Holtrop, J.,Gherardi, E.,Vande Woude, G.,Xu, H.E. Structural basis for agonism and antagonism of hepatocyte growth factor. Proc.Natl.Acad.Sci.USA, 107:13264-13269, 2010 Cited by PubMed: 20624990 DOI: 10.1073/pnas.1005183107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation