3HMH
Crystal structure of the second bromodomain of human TBP-associated factor RNA polymerase 1-like (TAF1L)
Summary for 3HMH
Entry DOI | 10.2210/pdb3hmh/pdb |
Related | 3HME 3HMF |
Descriptor | Transcription initiation factor TFIID 210 kDa subunit (2 entities in total) |
Functional Keywords | mgc134910, taf2a2, structural genomics consortium, sgc, bromodomain, cell cycle, disulfide bond, dna-binding, nucleus, transcription, transcription regulation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (By similarity): Q8IZX4 |
Total number of polymer chains | 1 |
Total formula weight | 18023.25 |
Authors | Filippakopoulos, P.,Picaud, S.,Keates, T.,Zhang, Y.,Pike, A.C.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2009-05-29, release date: 2009-06-23, Last modification date: 2023-11-01) |
Primary citation | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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