3HMF

Crystal Structure of the second Bromodomain of Human Poly-bromodomain containing protein 1 (PB1)

Summary for 3HMF

Entry DOI	10.2210/pdb3hmf/pdb
Related	3HME 3HMH
Descriptor	Protein polybromo-1, ZINC ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	pb1, polybromo 1 isoform 1, baf180, polybromo-1d, pbrm1, brg1-associated factor 180, bromodomain, chromatin regulator, dna-binding, nucleus, phosphoprotein, transcription, transcription regulation, structural genomics, structural genomics consortium, sgc
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q86U86
Total number of polymer chains	1
Total formula weight	13495.09
Authors	Filippakopoulos, P.,Picaud, S.,Keates, T.,Muniz, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2009-05-29, release date: 2009-06-23, Last modification date: 2023-11-01)
Primary citation	Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331 DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.63 Å)

Structure validation