3HMH

Crystal structure of the second bromodomain of human TBP-associated factor RNA polymerase 1-like (TAF1L)

Summary for 3HMH

Entry DOI	10.2210/pdb3hmh/pdb
Related	3HME 3HMF
Descriptor	Transcription initiation factor TFIID 210 kDa subunit (2 entities in total)
Functional Keywords	mgc134910, taf2a2, structural genomics consortium, sgc, bromodomain, cell cycle, disulfide bond, dna-binding, nucleus, transcription, transcription regulation
Biological source	Homo sapiens (human)
Cellular location	Nucleus (By similarity): Q8IZX4
Total number of polymer chains	1
Total formula weight	18023.25
Authors	Filippakopoulos, P.,Picaud, S.,Keates, T.,Zhang, Y.,Pike, A.C.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2009-05-29, release date: 2009-06-23, Last modification date: 2023-11-01)
Primary citation	Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331 DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation