3HMH

Crystal structure of the second bromodomain of human TBP-associated factor RNA polymerase 1-like (TAF1L)

3HMH の概要

• エントリーDOI: 10.2210/pdb3hmh/pdb
• 関連するPDBエントリー: 3HME 3HMF
• 分子名称: Transcription initiation factor TFIID 210 kDa subunit (2 entities in total)
• 機能のキーワード: mgc134910, taf2a2, structural genomics consortium, sgc, bromodomain, cell cycle, disulfide bond, dna-binding, nucleus, transcription, transcription regulation
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus (By similarity): Q8IZX4
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18023.25

構造登録者

Filippakopoulos, P.,Picaud, S.,Keates, T.,Zhang, Y.,Pike, A.C.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2009-05-29, 公開日: 2009-06-23, 最終更新日: 2023-11-01)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S.; Histone recognition and large-scale structural analysis of the human bromodomain family.; Cell(Cambridge,Mass.), 149:214-231, 2012; PubMed: 22464331; DOI: 10.1016/j.cell.2012.02.013

実験手法

X-RAY DIFFRACTION (2.05 Å)