3HL4
Crystal structure of a mammalian CTP:phosphocholine cytidylyltransferase with CDP-choline
Summary for 3HL4
Entry DOI | 10.2210/pdb3hl4/pdb |
Descriptor | Choline-phosphate cytidylyltransferase A, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM, GLYCEROL, ... (5 entities in total) |
Functional Keywords | cytidylyltransferase, rossmann fold, phospholipid synthesis, phosphatidylcholine, phosphocholine, ctp, cdp-choline, amphitropic protein, lipid metabolism, nucleotidyltransferase, phosphoprotein, transferase |
Biological source | Rattus norvegicus (rat) |
Cellular location | Cytoplasm, cytosol: P19836 |
Total number of polymer chains | 2 |
Total formula weight | 54975.05 |
Authors | Lee, J.,Paetzel, M.,Cornell, R.B. (deposition date: 2009-05-26, release date: 2009-09-22, Last modification date: 2024-02-21) |
Primary citation | Lee, J.,Johnson, J.E.,Ding, Z.,Paetzel, M.,Cornell, R.B. Crystal Structure of a mammalian CTP: Phosphocholine cytidylyltransferase catalytic domain reveals novel active site residues within a highly conserved nucleotidyl-transferase fold J.Biol.Chem., 284:33535-33548, 2009 Cited by PubMed: 19783652DOI: 10.1074/jbc.M109.053363 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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