3HL2

The crystal structure of the human SepSecS-tRNASec complex

Summary for 3HL2

• Entry DOI: 10.2210/pdb3hl2/pdb
• Descriptor: O-phosphoseryl-tRNA(Sec) selenium transferase, tRNASec, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ... (6 entities in total)
• Functional Keywords: selenocysteine, trnasec, sepsecs, protein-rna complex, alternative splicing, cytoplasm, protein biosynthesis, pyridoxal phosphate, selenium, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : Q9HD40
• Total number of polymer chains: 5
• Total formula weight: 254128.03

Authors

Palioura, S.,Steitz, T.A.,Soll, D.,Simonovic, M. (deposition date: 2009-05-26, release date: 2009-10-06, Last modification date: 2023-09-06)

• Primary citation: Palioura, S.,Sherrer, R.L.,Steitz, T.A.,Soll, D.,Simonovic, M.; The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation.; Science, 325:321-325, 2009; PubMed: 19608919; DOI: 10.1126/science.1173755

Experimental method

X-RAY DIFFRACTION (2.81 Å)