3HL2

The crystal structure of the human SepSecS-tRNASec complex

3HL2 の概要

• エントリーDOI: 10.2210/pdb3hl2/pdb
• 分子名称: O-phosphoseryl-tRNA(Sec) selenium transferase, tRNASec, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ... (6 entities in total)
• 機能のキーワード: selenocysteine, trnasec, sepsecs, protein-rna complex, alternative splicing, cytoplasm, protein biosynthesis, pyridoxal phosphate, selenium, transferase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm : Q9HD40
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 254128.03

構造登録者

Palioura, S.,Steitz, T.A.,Soll, D.,Simonovic, M. (登録日: 2009-05-26, 公開日: 2009-10-06, 最終更新日: 2023-09-06)

• 主引用文献: Palioura, S.,Sherrer, R.L.,Steitz, T.A.,Soll, D.,Simonovic, M.; The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation.; Science, 325:321-325, 2009; PubMed: 19608919; DOI: 10.1126/science.1173755

実験手法

X-RAY DIFFRACTION (2.81 Å)