3HGX

Crystal Structure of Pseudomonas aeruginosa Isochorismate-Pyruvate Lyase K42A mutant in complex with salicylate and pyruvate

Summary for 3HGX

• Entry DOI: 10.2210/pdb3hgx/pdb
• Related: 2H9C 2H9D 3HGW
• Descriptor: Salicylate biosynthesis protein pchB, 2-HYDROXYBENZOIC ACID, PYRUVIC ACID, ... (4 entities in total)
• Functional Keywords: siderophore biosynthesis, pyochelin, isochorismate-pyruvate lyase, chorismate mutase, pchb, lyase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 23230.29

Authors

Luo, Q.,Lamb, A.L. (deposition date: 2009-05-14, release date: 2009-06-30, Last modification date: 2023-11-15)

• Primary citation: Luo, Q.,Olucha, J.,Lamb, A.L.; Structure-function analyses of isochorismate-pyruvate lyase from Pseudomonas aeruginosa suggest differing catalytic mechanisms for the two pericyclic reactions of this bifunctional enzyme.; Biochemistry, 48:5239-5245, 2009; PubMed: 19432488; DOI: 10.1021/bi900456e

Experimental method