3HG1
Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor
Summary for 3HG1
Entry DOI | 10.2210/pdb3hg1/pdb |
Descriptor | MHC class I antigen, Beta-2-microglobulin, CANCER/MART-1, ... (8 entities in total) |
Functional Keywords | t-cell receptor, cdr3, phage display, melan-1, mart-1, immune system, disulfide bond, transmembrane, disease mutation, glycation, glycoprotein, immune response, immunoglobulin domain, mhc i, pyrrolidone carboxylic acid, secreted |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P61769 |
Total number of polymer chains | 5 |
Total formula weight | 93827.93 |
Authors | Cole, D.K.,Yuan, F.,Rizkallah, P.J.,Miles, J.J.,Gostick, E.,Price, D.A.,Gao, G.F.,Jakobsen, B.K.,Sewell, A.K. (deposition date: 2009-05-13, release date: 2009-07-28, Last modification date: 2014-04-09) |
Primary citation | Cole, D.K.,Yuan, F.,Rizkallah, P.J.,Miles, J.J.,Gostick, E.,Price, D.A.,Gao, G.F.,Jakobsen, B.K.,Sewell, A.K. Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor. J.Biol.Chem., 284:27281-27289, 2009 Cited by PubMed: 19605354DOI: 10.1074/jbc.M109.022509 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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