3HG1

Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor

3HG1 の概要

• エントリーDOI: 10.2210/pdb3hg1/pdb
• 分子名称: MHC class I antigen, Beta-2-microglobulin, CANCER/MART-1, ... (8 entities in total)
• 機能のキーワード: t-cell receptor, cdr3, phage display, melan-1, mart-1, immune system, disulfide bond, transmembrane, disease mutation, glycation, glycoprotein, immune response, immunoglobulin domain, mhc i, pyrrolidone carboxylic acid, secreted
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P61769
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 93827.93

構造登録者

Cole, D.K.,Yuan, F.,Rizkallah, P.J.,Miles, J.J.,Gostick, E.,Price, D.A.,Gao, G.F.,Jakobsen, B.K.,Sewell, A.K. (登録日: 2009-05-13, 公開日: 2009-07-28, 最終更新日: 2014-04-09)

• 主引用文献: Cole, D.K.,Yuan, F.,Rizkallah, P.J.,Miles, J.J.,Gostick, E.,Price, D.A.,Gao, G.F.,Jakobsen, B.K.,Sewell, A.K.; Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.; J.Biol.Chem., 284:27281-27289, 2009; PubMed: 19605354; DOI: 10.1074/jbc.M109.022509

実験手法

X-RAY DIFFRACTION (3 Å)