3HFA

Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant

Summary for 3HFA

Entry DOI	10.2210/pdb3hfa/pdb
Related	2FHG 2FHH 3H6F 3H6I
Descriptor	Proteasome (Beta subunit) PrcB, Proteasome (Alpha subunit) PrcA, DIMETHYLFORMAMIDE, ... (4 entities in total)
Functional Keywords	mycobacterium tuberculosis, proteasome endopeptidase, open gate, mutant, hydrolase, proteasome
Biological source	Mycobacterium tuberculosis More
Total number of polymer chains	28
Total formula weight	721686.80
Authors	Li, D.,Li, H. (deposition date: 2009-05-11, release date: 2009-09-15, Last modification date: 2023-11-29)
Primary citation	Lin, G.,Li, D.,de Carvalho, L.P.,Deng, H.,Tao, H.,Vogt, G.,Wu, K.,Schneider, J.,Chidawanyika, T.,Warren, J.D.,Li, H.,Nathan, C. Inhibitors selective for mycobacterial versus human proteasomes. Nature, 461:621-626, 2009 Cited by PubMed: 19759536 DOI: 10.1038/nature08357 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.504 Å)

Structure validation