3HFA

Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (H, C, E, G, J...)	Proteasome (Beta subunit) PrcB	polymer	240	25274.3	14	UniProt (O33245) Pfam (PF00227) UniProt (by SIFTS) (P9WHU1)	Mycobacterium tuberculosis	Proteasome, beta subunit
2	AA, BA, O, P, Q... (D, A, B, F, I...)	Proteasome (Alpha subunit) PrcA	polymer	240	25972.0	14	UniProt (O33244) Pfam (PF00227) UniProt (by SIFTS) (P9WHU1)	Mycobacterium tuberculosis
3	AB, AC, BB, BC, CA... (V, U, H, X, W...)	DIMETHYLFORMAMIDE	non-polymer		73.1	58	Chemie (DMF)
4	AD, BD, CD, DD, ED... (I, K, M, O, Q...)	water	water		18.0	2109	Chemie (HOH)

Sequence modifications

H, C, E, G, J, L, N, P, R, T, V, X, Z, 2: 301 - 534 (UniProt: O33245)

PDB	External Database	Details
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag

D, A, B, F, I, K, M, O, Q, S, U, W, Y, 1: 10 - 248 (UniProt: O33244)

PDB	External Database	Details
Met 9	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	28
	Total formula weight	717447.3
Non-Polymers*	Number of molecules	58
	Total formula weight	4239.5
All*	Total formula weight	721686.8

*Water molecules are not included.