3H8V
Human Ubiquitin-activating Enzyme 5 in Complex with ATP
Summary for 3H8V
Entry DOI | 10.2210/pdb3h8v/pdb |
Related | 3GUC |
Descriptor | Ubiquitin-like modifier-activating enzyme 5, ZINC ION, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | rossmann fold, atp-binding, ubl conjugation pathway, transferase, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q9GZZ9 |
Total number of polymer chains | 2 |
Total formula weight | 64969.89 |
Authors | Walker, J.R.,Bacik, J.P.,Rastgoo, N.,Weigelt, J.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2009-04-29, release date: 2009-05-26, Last modification date: 2023-09-06) |
Primary citation | Bacik, J.P.,Walker, J.R.,Ali, M.,Schimmer, A.D.,Dhe-Paganon, S. Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme. J.Biol.Chem., 285:20273-20280, 2010 Cited by PubMed: 20368332DOI: 10.1074/jbc.M110.102921 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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