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3H6I

Crystal Structure of Mycobacterium Tuberculosis Proteasome Modified by inhibitor GL1

Summary for 3H6I
Entry DOI10.2210/pdb3h6i/pdb
Related2FHG 2FHH 3H6F
DescriptorProteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB, DIMETHYLFORMAMIDE, ... (4 entities in total)
Functional Keywordsbinding sites, oxazolidin-2-one, mycobacterium tuberculosis, protease inhibitors, proteasome endopeptidase complex, protein subunits, substrate specificity, hydrolase, proteasome
Biological sourceMycobacterium tuberculosis
More
Cellular locationCytoplasm (By similarity): O33244 O33245
Total number of polymer chains28
Total formula weight738413.75
Authors
Li, D.,Li, H.,Lin, G. (deposition date: 2009-04-23, release date: 2009-09-15, Last modification date: 2023-11-22)
Primary citationLin, G.,Li, D.,de Carvalho, L.P.,Deng, H.,Tao, H.,Vogt, G.,Wu, K.,Schneider, J.,Chidawanyika, T.,Warren, J.D.,Li, H.,Nathan, C.
Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461:621-626, 2009
Cited by
PubMed: 19759536
DOI: 10.1038/nature08357
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.43 Å)
Structure validation

217705

數據於2024-03-27公開中

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