3H6I

Crystal Structure of Mycobacterium Tuberculosis Proteasome Modified by inhibitor GL1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, D, F, I...	Proteasome (Alpha subunit) PrcA	polymer	248	26911.0	14	UniProt (O33244) Pfam (PF00227) UniProt (by SIFTS) (P9WHU1) In PDB	Mycobacterium tuberculosis
2	C, E, G, H, J...	Proteasome (Beta subunit) PrcB	polymer	240	25300.3	14	UniProt (O33245) Pfam (PF00227) UniProt (by SIFTS) (P9WHT9) In PDB	Mycobacterium tuberculosis	Proteasome, beta subunit
3	F, N, U, G, A...	DIMETHYLFORMAMIDE	non-polymer		73.1	102	Chemie (DMF)
4		water	water		18.0	2381	Chemie (HOH)

Sequence modifications

C, E, G, H, J, L, N, P, R, T, V, X, Z, 2: 302 - 534 (UniProt: O33245)

PDB	External Database	Details
Ozt 301	-	insertion
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	28
	Total formula weight	730958.2
Non-Polymers*	Number of molecules	102
	Total formula weight	7455.6
All*	Total formula weight	738413.7

*Water molecules are not included.