3H3G

Crystal structure of the extracellular domain of the human parathyroid hormone receptor (PTH1R) in complex with parathyroid hormone-related protein (PTHrP)

3H3G の概要

• エントリーDOI: 10.2210/pdb3h3g/pdb
• 関連するPDBエントリー: 3C4M
• 関連するBIRD辞書のPRD_ID: PRD_900001
• 分子名称: Fusion protein of Maltose-binding periplasmic domain and human parathyroid hormone receptor extracellular domain, Parathyroid hormone-related protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: gpcr, extracellular domain, pthrp, pth, pthr1, sugar transport, transport, hormone, membrane protein
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63404.48

構造登録者

Pioszak, A.A.,Xu, H.E. (登録日: 2009-04-16, 公開日: 2009-08-11, 最終更新日: 2023-09-06)

• 主引用文献: Pioszak, A.A.,Parker, N.R.,Gardella, T.J.,Xu, H.E.; Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides.; J.Biol.Chem., 284:28382-28391, 2009; PubMed: 19674967; DOI: 10.1074/jbc.M109.022905

実験手法

X-RAY DIFFRACTION (1.94 Å)