3H2X

Crystal Structure of The Human Lymphoid Tyrosine Phosphatase Catalytic Domain

3H2X の概要

• エントリーDOI: 10.2210/pdb3h2x/pdb
• 分子名称: Tyrosine-protein phosphatase non-receptor type 22, PHOSPHATE ION (3 entities in total)
• 機能のキーワード: sh2-like fold, alternative splicing, cytoplasm, hydrolase, polymorphism, protein phosphatase, systemic lupus erythematosus
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm (By similarity): Q9Y2R2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36089.75

構造登録者

Tsai, S.J.,Sen, U. (登録日: 2009-04-14, 公開日: 2009-06-02, 最終更新日: 2023-09-06)

• 主引用文献: Tsai, S.J.,Sen, U.,Zhao, L.,Greenleaf, W.B.,Dasgupta, J.,Fiorillo, E.,Orru, V.,Bottini, N.,Chen, X.S.; Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation .; Biochemistry, 48:4838-4845, 2009; PubMed: 19371084; DOI: 10.1021/bi900166y

実験手法

X-RAY DIFFRACTION (2.2 Å)