3GUI

T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--Apo structure

Summary for 3GUI

Entry DOI	10.2210/pdb3gui/pdb
Related	3GUJ 3GUK 3GUL 3GUM 3GUN 3GUO 3GUP
Descriptor	Lysozyme, BETA-MERCAPTOETHANOL, CARBONATE ION, ... (6 entities in total)
Functional Keywords	t4 lysozyme, apolar cavity, buried charge, ligand binding, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
Biological source	Enterobacteria phage T4
Cellular location	Host cytoplasm : P00720
Total number of polymer chains	1
Total formula weight	19183.11
Authors	Liu, L.,Matthews, B.W. (deposition date: 2009-03-30, release date: 2009-08-25, Last modification date: 2023-09-06)
Primary citation	Liu, L.,Baase, W.A.,Michael, M.M.,Matthews, B.W. Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme. Biochemistry, 48:8842-8851, 2009 Cited by PubMed: 19663503 DOI: 10.1021/bi900685j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation