3GS6

Vibrio Cholerea family 3 glycoside hydrolase (NagZ)in complex with N-butyryl-PUGNAc

Summary for 3GS6

• Entry DOI: 10.2210/pdb3gs6/pdb
• Related: 1TR9 1Y65 2OXN 3GSM
• Descriptor: Beta-hexosaminidase, [[(3R,4R,5S,6R)-3-(BUTANOYLAMINO)-4,5-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YLIDENE]AMINO] N-PHENYLCARBAMATE, GLYCEROL, ... (4 entities in total)
• Functional Keywords: glycoside hydrolase family 3, cell cycle, cell division, cell shape, cell wall biogenesis/degradation, glycosidase, hydrolase, peptidoglycan synthesis
• Biological source: Vibrio cholerae
• Cellular location: Cytoplasm (By similarity): Q9KU37
• Total number of polymer chains: 1
• Total formula weight: 38280.42

Authors

Balcewich, M.D.,Mark, B.L. (deposition date: 2009-03-26, release date: 2009-06-30, Last modification date: 2023-09-06)

• Primary citation: Balcewich, M.D.,Stubbs, K.A.,He, Y.,James, T.W.,Davies, G.J.,Vocadlo, D.J.,Mark, B.L.; Insight into a strategy for attenuating AmpC-mediated beta-lactam resistance: structural basis for selective inhibition of the glycoside hydrolase NagZ.; Protein Sci., 18:1541-1551, 2009; PubMed: 19499593; DOI: 10.1002/pro.137

Experimental method

X-RAY DIFFRACTION (2.3 Å)