3GD7

Crystal structure of human NBD2 complexed with N6-Phenylethyl-ATP (P-ATP)

3GD7 の概要

• エントリーDOI: 10.2210/pdb3gd7/pdb
• 関連するPDBエントリー: 1MT0 1Q12 1XMI 2BBT 2PZE 2PZF
• 分子名称: Fusion complex of Cystic fibrosis transmembrane conductance regulator, residues 1193-1427 and Maltose/maltodextrin import ATP-binding protein malK, residues 219-371, N-(2-phenylethyl)adenosine 5'-(tetrahydrogen triphosphate) (3 entities in total)
• 機能のキーワード: cftr, abc transporter, nucleotide binding domain, nbd, atp, p-atp, n6-phenylethyl-atp, atp-binding, chloride channel, ion transport, ionic channel, transport, cell inner membrane, cell membrane, hydrolase, sugar transport
• 由来する生物種: Homo sapiens (human,bacteria); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 176520.44

構造登録者

Atwell, S.,Antonysamy, S.,Conners, K.,Emtage, S.,Gheyi, T.,Lewis, H.A.,Lu, F.,Sauder, J.M.,Wasserman, S.R.,Zhao, X. (登録日: 2009-02-23, 公開日: 2010-03-02, 最終更新日: 2023-09-06)

• 主引用文献: Atwell, S.,Antonysamy, S.,Guggino, W.B.,Conners, K.,Emtage, S.,Gheyi, T.,Hunt, J.F.,Lewis, H.A.,Lu, F.,Sauder, J.M.,Weber, P.C.,Wetmore, D.,Zhao, X.; Crystal structure of human NBD2 complexed with N6-Phenylethyl-ATP (P-ATP); To be Published,

実験手法

X-RAY DIFFRACTION (2.7 Å)