3GD7
Crystal structure of human NBD2 complexed with N6-Phenylethyl-ATP (P-ATP)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005524 | molecular_function | ATP binding |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0022857 | molecular_function | transmembrane transporter activity |
| C | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005524 | molecular_function | ATP binding |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0022857 | molecular_function | transmembrane transporter activity |
| D | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE B44 A 1 |
| Chain | Residue |
| A | HOH5 |
| A | THR1252 |
| A | LEU1260 |
| B | PHE1296 |
| B | SER1297 |
| A | TYR1219 |
| A | ILE1226 |
| A | THR1246 |
| A | GLY1247 |
| A | SER1248 |
| A | GLY1249 |
| A | LYS1250 |
| A | SER1251 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE B44 B 2 |
| Chain | Residue |
| A | PHE1294 |
| A | PHE1296 |
| B | HOH6 |
| B | HOH128 |
| B | HOH145 |
| B | HOH189 |
| B | TYR1219 |
| B | ILE1226 |
| B | THR1246 |
| B | GLY1247 |
| B | SER1248 |
| B | GLY1249 |
| B | LYS1250 |
| B | SER1251 |
| B | THR1252 |
| B | LEU1260 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE B44 C 3 |
| Chain | Residue |
| C | HOH7 |
| C | TYR1219 |
| C | ILE1226 |
| C | ARG1245 |
| C | THR1246 |
| C | GLY1247 |
| C | SER1248 |
| C | GLY1249 |
| C | LYS1250 |
| C | SER1251 |
| C | THR1252 |
| C | SER1255 |
| D | PHE1294 |
| D | PHE1296 |
| D | SER1297 |
| D | LYS1302 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE B44 D 4 |
| Chain | Residue |
| C | PHE1294 |
| C | PHE1296 |
| D | HOH8 |
| D | TYR1219 |
| D | ILE1226 |
| D | THR1246 |
| D | GLY1247 |
| D | SER1248 |
| D | GLY1249 |
| D | LYS1250 |
| D | SER1251 |
| D | THR1252 |
| D | LEU1260 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3GD7 |
| Chain | Residue | Details |
| A | TYR1219 | |
| B | TYR1219 | |
| C | TYR1219 | |
| D | TYR1219 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434, ECO:0007744|PDB:3GD7 |
| Chain | Residue | Details |
| A | GLY1244 | |
| B | GLY1244 | |
| C | GLY1244 | |
| D | GLY1244 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:22119790 |
| Chain | Residue | Details |
| A | CYS1395 | |
| B | CYS1395 | |
| C | CYS1395 | |
| D | CYS1395 |
