3GD7

Crystal structure of human NBD2 complexed with N6-Phenylethyl-ATP (P-ATP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Fusion complex of Cystic fibrosis transmembrane conductance regulator, residues 1193-1427 and Maltose/maltodextrin import ATP-binding protein malK, residues 219-371	polymer	390	43518.8	4	UniProt (P13569) UniProt (P68187) Pfam (PF00005) Pfam (PF08402)	Homo sapiens (human bacteria)	CFTR, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7
2	E, F, G, H (A, B, C, D)	N-(2-phenylethyl)adenosine 5'-(tetrahydrogen triphosphate)	non-polymer		611.3	4	Chemie (B44)
3	I, J, K, L (A, B, C, D)	water	water		18.0	254	Chemie (HOH)

Sequence modifications

A, B, C, D: 1193 - 1427 (UniProt: P13569)

PDB	External Database	Details
Ser 1191	-	expression tag
Leu 1192	-	expression tag
Glu 1280	Gln 1280	engineered mutation
Asn 1307	Tyr 1307	engineered mutation
Ala 1308	Glu 1308	engineered mutation
Ala 1309	Gln 1309	engineered mutation
His 1310	Trp 1310	engineered mutation
Ala 1402	His 1402	engineered mutation
Asp 1411	Gln 1411	engineered mutation

A, B, C, D: 1428 - 1580 (UniProt: P68187)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	174075.1
Non-Polymers*	Number of molecules	4
	Total formula weight	2445.3
All*	Total formula weight	176520.4

*Water molecules are not included.