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3GCU

Human P38 MAP kinase in complex with RL48

Summary for 3GCU
Entry DOI10.2210/pdb3gcu/pdb
Related3GCQ 3GCS
DescriptorMitogen-activated protein kinase 14, 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea, octyl beta-D-glucopyranoside, ... (5 entities in total)
Functional Keywordsdfg-out, type ii, atp-binding, kinase, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight84916.03
Authors
Gruetter, C.,Simard, J.R.,Getlik, M.,Rauh, D. (deposition date: 2009-02-22, release date: 2009-06-09, Last modification date: 2023-09-06)
Primary citationSimard, J.R.,Getlik, M.,Grutter, C.,Pawar, V.,Wulfert, S.,Rabiller, M.,Rauh, D.
Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors.
J.Am.Chem.Soc., 131:13286-13296, 2009
Cited by
PubMed: 19572644
DOI: 10.1021/ja902010p
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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