3GBA
X-ray structure of iGluR5 ligand-binding core (S1S2) in complex with dysiherbaine at 1.35A resolution
Summary for 3GBA
Entry DOI | 10.2210/pdb3gba/pdb |
Related | 1YCJ 3GBB |
Descriptor | Glutamate receptor, ionotropic kainate 1, (2R,3aR,6S,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6-hydroxy-7-(methylamino)hexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid, SULFATE ION, ... (6 entities in total) |
Functional Keywords | ionotropic glutamate receptors, iglur5, ligand-binding core, agonist, membrane protein |
Biological source | Rattus norvegicus (rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P22756 |
Total number of polymer chains | 4 |
Total formula weight | 118190.31 |
Authors | Frydenvang, K.,Naur, P.,Gajhede, M.,Kastrup, J.S. (deposition date: 2009-02-19, release date: 2009-03-17, Last modification date: 2023-11-01) |
Primary citation | Frydenvang, K.,Lash, L.L.,Naur, P.,Postila, P.A.,Pickering, D.S.,Smith, C.M.,Gajhede, M.,Sasaki, M.,Sakai, R.,Pentikainen, O.T.,Swanson, G.T.,Kastrup, J.S. Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine J.Biol.Chem., 284:14219-14229, 2009 Cited by PubMed: 19297335DOI: 10.1074/jbc.M808547200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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