3GBA
X-ray structure of iGluR5 ligand-binding core (S1S2) in complex with dysiherbaine at 1.35A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
| D | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| D | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15710405, ECO:0007744|PDB:1YCJ |
| Chain | Residue | Details |
| A | LYS103 | |
| C | PHE105 | |
| C | LYS156 | |
| C | MET157 | |
| D | LYS103 | |
| D | PHE105 | |
| D | LYS156 | |
| D | MET157 | |
| A | PHE105 | |
| A | LYS156 | |
| A | MET157 | |
| B | LYS103 | |
| B | PHE105 | |
| B | LYS156 | |
| B | MET157 | |
| C | LYS103 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15710405, ECO:0000269|PubMed:15721240, ECO:0007744|PDB:1YCJ |
| Chain | Residue | Details |
| A | ILE110 | |
| A | THR205 | |
| B | ILE110 | |
| B | THR205 | |
| C | ILE110 | |
| C | THR205 | |
| D | ILE110 | |
| D | THR205 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by PKC => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE177 | |
| B | ILE177 | |
| C | ILE177 | |
| D | ILE177 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000255 |
| Chain | Residue | Details |
| A | SER213 | |
| B | SER213 | |
| C | SER213 | |
| D | SER213 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE11 | |
| D | ILE11 | |
| D | MET18 | |
| D | VAL218 | |
| A | MET18 | |
| A | VAL218 | |
| B | ILE11 | |
| B | MET18 | |
| B | VAL218 | |
| C | ILE11 | |
| C | MET18 | |
| C | VAL218 |
