3GBA
X-ray structure of iGluR5 ligand-binding core (S1S2) in complex with dysiherbaine at 1.35A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor, ionotropic kainate 1 | polymer | 257 | 29108.5 | 4 | UniProt (P22756) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (rat) | Glutamate receptor 5, GluR-5, GluR5 |
| 2 | E, I, M, O (A, B, C, D) | (2R,3aR,6S,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6-hydroxy-7-(methylamino)hexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid | non-polymer | 304.3 | 4 | Chemie (DYH) | |||
| 3 | F, J (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | G, K, N (A, B, C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | H, L (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 1441 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 116 (UniProt: P22756)
A, B, C, D: 119 - 257 (UniProt: P22756)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Gly 34 | Ala 462 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | linker |
| Thr 118 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116433.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1756.5 | |
| All* | Total formula weight | 118190.3 |
