3G1N

Catalytic domain of the human E3 ubiquitin-protein ligase HUWE1

3G1N の概要

• エントリーDOI: 10.2210/pdb3g1n/pdb
• 分子名称: E3 ubiquitin-protein ligase HUWE1, SODIUM ION (3 entities in total)
• 機能のキーワード: alpha and beta protein (a + b), e3 ligase, hect domain, ubl-conjugation pathway, alternative splicing, chromosomal rearrangement, cytoplasm, differentiation, disease mutation, dna-binding, ligase, mental retardation, nucleus, phosphoprotein, ubl conjugation pathway, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q7Z6Z7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 91102.98

構造登録者

Walker, J.R.,Qiu, L.,Li, Y.,Davis, T.,Tempel, W.,Weigelt, J.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Botchkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (登録日: 2009-01-30, 公開日: 2009-02-17, 最終更新日: 2023-09-06)

• 主引用文献: Walker, J.R.,Qiu, L.,Li, Y.,Davis, T.,Tempel, W.,Weigelt, J.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Botchkarev, A.,Dhe-Paganon, S.; Hect Domain of Human HUWE1/MULE; To be Published,

実験手法

X-RAY DIFFRACTION (2.6 Å)