3FYP
Crystal structure of the quadruple mutant (N23C/C246S/D247E/P249A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis
Summary for 3FYP
Entry DOI | 10.2210/pdb3fyp/pdb |
Related | 2qkf |
Descriptor | 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase, CHLORIDE ION, GLYCEROL, ... (7 entities in total) |
Functional Keywords | manno-octulosonate, synthase, lipopolysaccharide, kdop, kdo8 kdops, kdo8ps, tim barrel, biosynthesis, transferase, lyase, lipopolysaccharide biosynthesis |
Biological source | Neisseria meningitidis serogroup B |
Cellular location | Cytoplasm (By similarity): Q9JZ55 |
Total number of polymer chains | 4 |
Total formula weight | 122445.22 |
Authors | Jameson, G.B.,Parker, E.J.,Cochrane, F.P.,Patchett, M.L. (deposition date: 2009-01-22, release date: 2009-03-31, Last modification date: 2023-09-06) |
Primary citation | Cochrane, F.C.,Cookson, T.V.,Jameson, G.B.,Parker, E.J. Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase J.Mol.Biol., 390:646-661, 2009 Cited by PubMed: 19447118DOI: 10.1016/j.jmb.2009.05.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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