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3FY2

Human EphA3 Kinase and Juxtamembrane Region Bound to Substrate KQWDNYEFIW

Summary for 3FY2
Entry DOI10.2210/pdb3fy2/pdb
Related1IR3 2GSF 2QOC 3FXX
DescriptorEphrin type-A receptor 3, peptide substrate (3 entities in total)
Functional Keywordsreceptor tyrosine kinase, juxtamembrane segment, structural genomics, peptide co-crystal structure, structural genomics consortium, sgc, atp-binding, cell membrane, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, receptor, secreted, transferase, transmembrane, tyrosine-protein kinase
Biological sourceHomo sapiens (Human)
More
Cellular locationIsoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Secreted : P29320
Total number of polymer chains2
Total formula weight43249.28
Authors
Davis, T.,Walker, J.R.,Mackenzie, F.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2009-01-21, release date: 2009-02-03, Last modification date: 2023-09-06)
Primary citationDavis, T.L.,Walker, J.R.,Allali-Hassani, A.,Parker, S.A.,Turk, B.E.,Dhe-Paganon, S.
Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases.
Febs J., 276:4395-4404, 2009
Cited by
PubMed: 19678838
DOI: 10.1111/j.1742-4658.2009.07147.x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

건을2024-03-27부터공개중

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