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3FXW

High resolution crystal structure of mitogen-activated protein kinase-activated protein kinase 3/inhibitor 2 complex

Summary for 3FXW
Entry DOI10.2210/pdb3fxw/pdb
Related3fhr
DescriptorMAP kinase-activated protein kinase 3, 2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE (3 entities in total)
Functional Keywordskinase domain fold, atp-binding, kinase, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus: Q16644
Total number of polymer chains1
Total formula weight38882.30
Authors
Cheng, R.K.Y.,Barker, J.,Palan, S.,Felicetti, B.,Whittaker, M.,Hesterkamp, T. (deposition date: 2009-01-21, release date: 2010-01-26, Last modification date: 2023-11-01)
Primary citationCheng, R.K.Y.,Barker, J.,Palan, S.,Felicetti, B.,Whittaker, M.,Hesterkamp, T.
High resolution crystal structure of mitogen-activated protein kinase-activated protein kinase 3/inhibitor 2 complex
To be Published,
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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