3FWO
The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin
Summary for 3FWO
Entry DOI | 10.2210/pdb3fwo/pdb |
Related | 1NKW |
Descriptor | 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside (3 entities in total) |
Functional Keywords | ribosome; large subunit; 50s; deinococcus radiodurans; x-ray structure; peptidyl-transferase, peptide bond formation, antibiotics, macrolides, ribosome |
Biological source | Deinococcus radiodurans R1 More |
Total number of polymer chains | 2 |
Total formula weight | 971904.39 |
Authors | Auerbach, T.,Mermershtain, I.,Bashan, A.,Davidovich, C.,Rozenberg, H.,Sherman, D.H.,Yonath, A. (deposition date: 2009-01-19, release date: 2010-01-19, Last modification date: 2024-02-21) |
Primary citation | Auerbach, T.,Mermershtain, I.,Bashan, A.,Davidovich, C.,Rozenberg, H.,Sherman, D.H.,Yonath, A. Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin Biotechnologia, 1:24-35, 2009 |
Experimental method | X-RAY DIFFRACTION (3.71 Å) |
Structure validation
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