3FUB

Crystal structure of GDNF-GFRalpha1 complex

3FUB の概要

• エントリーDOI: 10.2210/pdb3fub/pdb
• 関連するPDBエントリー: 2GH0 2v5e
• 分子名称: GDNF family receptor alpha-1, Glial cell line-derived neurotrophic factor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: gfralpha1, all alpha gdnf, cystine knot, cell membrane, glycoprotein, gpi-anchor, lipoprotein, membrane, receptor, cleavage on pair of basic residues, disease mutation, growth factor, hirschsprung disease, secreted, hormone
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 93346.88

構造登録者

Parkash, V.,Goldman, A. (登録日: 2009-01-14, 公開日: 2009-06-02, 最終更新日: 2023-09-06)

• 主引用文献: Parkash, V.,Goldman, A.; Comparison of GFL-GFRalpha complexes: further evidence relating GFL bend angle to RET signalling; Acta Crystallogr.,Sect.F, 65:551-558, 2009; PubMed: 19478429; DOI: 10.1107/S1744309109017722

実験手法

X-RAY DIFFRACTION (2.35 Å)