3FUB
Crystal structure of GDNF-GFRalpha1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | GDNF family receptor alpha-1 | polymer | 281 | 31113.3 | 2 | UniProt (Q62997) Pfam (PF02351) | Rattus norvegicus (rat) | GFR-alpha-1, GDNF receptor alpha, GDNFR-alpha, TGF-beta-related neurotrophic factor receptor 1, RET ligand 1 |
| 2 | B, D (B, D) | Glial cell line-derived neurotrophic factor | polymer | 134 | 15096.2 | 2 | UniProt (P39905) Pfam (PF00019) | Homo sapiens (human) | Astrocyte-derived trophic factor, ATF, hGDNF |
| 3 | E (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F, H, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | G (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | J (C) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 92419.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 503.5 | |
| All* | Total formula weight | 93346.9 |
