3FST
Crystal Structure of Escherichia coli Methylenetetrahydrofolate Reductase Mutant Phe223Leu at pH 7.4
Summary for 3FST
Entry DOI | 10.2210/pdb3fst/pdb |
Related | 3FSU |
Descriptor | 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE, MESO-ERYTHRITOL, ... (5 entities in total) |
Functional Keywords | tim barrel, flavin, reductase, amino-acid biosynthesis, fad, flavoprotein, methionine biosynthesis, nad, nadp, oxidoreductase |
Biological source | Escherichia coli K-12 |
Total number of polymer chains | 3 |
Total formula weight | 105312.47 |
Authors | Tanner, J.J. (deposition date: 2009-01-12, release date: 2009-08-25, Last modification date: 2023-09-06) |
Primary citation | Lee, M.N.,Takawira, D.,Nikolova, A.P.,Ballou, D.P.,Furtado, V.C.,Phung, N.L.,Still, B.R.,Thorstad, M.K.,Tanner, J.J.,Trimmer, E.E. Functional role for the conformationally mobile phenylalanine 223 in the reaction of methylenetetrahydrofolate reductase from Escherichia coli. Biochemistry, 48:7673-7685, 2009 Cited by PubMed: 19610625DOI: 10.1021/bi9007325 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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