3FOW

Plasmodium Purine Nucleoside Phosphorylase V66I-V73I-Y160F Mutant

Summary for 3FOW

• Entry DOI: 10.2210/pdb3fow/pdb
• Related: 1NW4
• Descriptor: Uridine phosphorylase, putative, PHOSPHATE ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, ... (4 entities in total)
• Functional Keywords: protein-inhibitor complex, phosphorylase, glycosyltransferase, transferase
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 2
• Total formula weight: 61940.58

Authors

Donaldson, T.,Zhan, C. (deposition date: 2009-01-02, release date: 2009-12-29, Last modification date: 2023-09-20)

• Primary citation: Donaldson, T.M.,Ting, L.M.,Zhan, C.,Shi, W.,Zheng, R.,Almo, S.C.,Kim, K.; Structural determinants of the 5'-methylthioinosine specificity of Plasmodium purine nucleoside phosphorylase.; Plos One, 9:e84384-e84384, 2014; PubMed: 24416224; DOI: 10.1371/journal.pone.0084384

Experimental method

X-RAY DIFFRACTION (2.8 Å)