3FN1
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.
Summary for 3FN1
| Entry DOI | 10.2210/pdb3fn1/pdb |
| Descriptor | NEDD8-activating enzyme E1 catalytic subunit, NEDD8-conjugating enzyme UBE2F (3 entities in total) |
| Functional Keywords | ligase, atp-binding, cell cycle, nucleotide-binding, ubl conjugation pathway |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 29961.57 |
| Authors | Huang, D.T.,Ayrault, O.,Hunt, H.W.,Taherbhoy, A.M.,Duda, D.M.,Scott, D.C.,Borg, L.A.,Neale, G.,Murray, P.J.,Roussel, M.F.,Schulman, B.A. (deposition date: 2008-12-22, release date: 2009-03-17, Last modification date: 2023-11-22) |
| Primary citation | Huang, D.T.,Ayrault, O.,Hunt, H.W.,Taherbhoy, A.M.,Duda, D.M.,Scott, D.C.,Borg, L.A.,Neale, G.,Murray, P.J.,Roussel, M.F.,Schulman, B.A. E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification Mol.Cell, 33:483-495, 2009 Cited by PubMed: 19250909DOI: 10.1016/j.molcel.2009.01.011 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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