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3FMZ

Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with non-retinoid ligand

3FMZ の概要
エントリーDOI10.2210/pdb3fmz/pdb
分子名称Retinol-binding protein 4, 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid (3 entities in total)
機能のキーワードretinol binding, disease mutation, retinol-binding, secreted, sensory transduction, transport, vision, vitamin a, transport protein
由来する生物種Homo sapiens (Human)
細胞内の位置Secreted: P02753
タンパク質・核酸の鎖数2
化学式量合計50025.70
構造登録者
Wang, Z.,Johnstone, S.,Walker, N.P. (登録日: 2008-12-22, 公開日: 2009-01-27, 最終更新日: 2011-07-13)
主引用文献Motani, A.,Wang, Z.,Conn, M.,Siegler, K.,Zhang, Y.,Liu, Q.,Johnstone, S.,Xu, H.,Thibault, S.,Wang, Y.,Fan, P.,Connors, R.,Le, H.,Xu, G.,Walker, N.,Shan, B.,Coward, P.
Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo.
J.Biol.Chem., 284:7673-7680, 2009
Cited by
PubMed: 19147488
DOI: 10.1074/jbc.M809654200
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (2.9 Å)
構造検証レポート
Validation report summary of 3fmz
検証レポート(詳細版)ダウンロードをダウンロード

217705

件を2024-03-27に公開中

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