3FL2

Crystal structure of the ring domain of the E3 ubiquitin-protein ligase UHRF1

Summary for 3FL2

• Entry DOI: 10.2210/pdb3fl2/pdb
• Related: 2FAZ 3BI7 3CLZ 3DB3 3DB4
• Descriptor: E3 ubiquitin-protein ligase UHRF1, ZINC ION (3 entities in total)
• Functional Keywords: cell cycle, dna damage, dna repair, ring finger domain, ligase, metal binding, dna replication, transcriptional silencing, chromatin, phosphorylation, transcription, transcription regulation, ubl conjugation, ubl conjugation pathway, zinc, zinc-finger, epigenetics, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q96T88
• Total number of polymer chains: 1
• Total formula weight: 14133.73

Authors

Walker, J.R.,Avvakumov, G.V.,Xue, S.,Li, Y.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2008-12-18, release date: 2009-01-20, Last modification date: 2023-09-06)

• Primary citation: Walker, J.R.,Avvakumov, G.V.,Xue, S.,Li, Y.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.; Structure of the Ring Domain of the E3 Ubiquitin-Protein Ligase Uhrf1; To be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)