3FL2

Crystal structure of the ring domain of the E3 ubiquitin-protein ligase UHRF1

3FL2 の概要

• エントリーDOI: 10.2210/pdb3fl2/pdb
• 関連するPDBエントリー: 2FAZ 3BI7 3CLZ 3DB3 3DB4
• 分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION (3 entities in total)
• 機能のキーワード: cell cycle, dna damage, dna repair, ring finger domain, ligase, metal binding, dna replication, transcriptional silencing, chromatin, phosphorylation, transcription, transcription regulation, ubl conjugation, ubl conjugation pathway, zinc, zinc-finger, epigenetics, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus : Q96T88
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14133.73

構造登録者

Walker, J.R.,Avvakumov, G.V.,Xue, S.,Li, Y.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (登録日: 2008-12-18, 公開日: 2009-01-20, 最終更新日: 2023-09-06)

• 主引用文献: Walker, J.R.,Avvakumov, G.V.,Xue, S.,Li, Y.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.; Structure of the Ring Domain of the E3 Ubiquitin-Protein Ligase Uhrf1; To be Published,

実験手法

X-RAY DIFFRACTION (1.75 Å)