3FHT

Crystal structure of human Dbp5 in complex with AMPPNP and RNA

3FHT の概要

• エントリーDOI: 10.2210/pdb3fht/pdb
• 関連するPDBエントリー: 3FHC
• 分子名称: ATP-dependent RNA helicase DDX19B, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: dbp5, dead-box helicase, rna dependent atpase, mrna export, nucleocytoplasmic transport, nup214, can, nup159, ddx19b, nuclear pore, gle1, atp-binding, helicase, hydrolase, membrane, mrna transport, nuclear pore complex, nucleotide-binding, nucleus, phosphoprotein, protein transport, rna-binding, translocation, transport, hydrolase-rna complex, hydrolase/rna
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm: Q9UMR2
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 100708.07

構造登録者

von Moeller, H.,Conti, E. (登録日: 2008-12-10, 公開日: 2009-02-17, 最終更新日: 2023-11-01)

• 主引用文献: von Moeller, H.,Basquin, C.,Conti, E.; The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner; Nat.Struct.Mol.Biol., 16:247-254, 2009; PubMed: 19219046; DOI: 10.1038/nsmb.1561

実験手法

X-RAY DIFFRACTION (2.2 Å)