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3FEX

Crystal structure of the CBC-importin alpha complex.

Summary for 3FEX
Entry DOI10.2210/pdb3fex/pdb
Related3FEX 3FEY
DescriptorNuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, Importin subunit alpha-2 (3 entities in total)
Functional Keywordscap binding complex, importin alpha, nuclear transport, coiled coil, mrna transport, nucleus, phosphoprotein, rna-binding, acetylation, cytoplasm, host-virus interaction, translation, protein transport
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus: Q09161 P52298
Cytoplasm: P52292
Total number of polymer chains3
Total formula weight160767.96
Authors
Dias, S.M.G.,Ambrosio, A.L.B.,Cerione, R.A. (deposition date: 2008-12-01, release date: 2009-08-11, Last modification date: 2023-09-06)
Primary citationDias, S.M.,Wilson, K.F.,Rojas, K.S.,Ambrosio, A.L.,Cerione, R.A.
The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16:930-937, 2009
Cited by
PubMed: 19668212
DOI: 10.1038/nsmb.1649
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.549 Å)
Structure validation

217705

数据于2024-03-27公开中

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