3FER

Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.

Summary for 3FER

• Entry DOI: 10.2210/pdb3fer/pdb
• Descriptor: Filamin-B, ACETIC ACID (3 entities in total)
• Functional Keywords: x-ray nesg hr5571a actin-binding domain, structural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, actin-binding, alternative splicing, cytoplasm, cytoskeleton, developmental protein, differentiation, disease mutation, dwarfism, myogenesis, phosphoprotein, polymorphism, actin binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Cytoplasm, cell cortex. Isoform 2: Cytoplasm, cytoskeleton. Isoform 3: Cytoplasm, cytoskeleton. Isoform 6: Cytoplasm, cytoskeleton: O75369
• Total number of polymer chains: 4
• Total formula weight: 122279.78

Authors

Kuzin, A.P.,Abashidze, M.,Seetharaman, R.,Shastry, R.,Sahdev, S.,Ciccosanti, C.,Xiao, R.,Everett, J.K.,Huang, Y.,Acton, T.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2008-11-30, release date: 2009-01-06, Last modification date: 2023-11-22)

• Primary citation: Kuzin, A.P.,Abashidze, M.,Seetharaman, R.,Shastry, R.,Sahdev, S.,Ciccosanti, C.,Xiao, R.,Everett, J.K.,Huang, Y.,Acton, T.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F.; Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.; To be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)