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3FDE

Mouse UHRF1 SRA domain bound with hemi-methylated CpG DNA, crystal structure in space group C222(1) at 1.4 A resolution

Summary for 3FDE
Entry DOI10.2210/pdb3fde/pdb
Related2ZO0 2ZO1 2ZO2 3F8I 3F8J
DescriptorE3 ubiquitin-protein ligase UHRF1, 5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3', 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', ... (7 entities in total)
Functional Keywordssra domain, base flipping, dna cpg methylation, cell cycle, developmental protein, dna damage, dna repair, dna-binding, ligase, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation, ubl conjugation pathway, zinc, zinc-finger
Biological sourceMus musculus
More
Cellular locationNucleus: Q8VDF2
Total number of polymer chains6
Total formula weight63970.50
Authors
Hashimoto, H.,Horton, J.R.,Zhang, X.,Cheng, X. (deposition date: 2008-11-25, release date: 2009-01-06, Last modification date: 2023-12-27)
Primary citationHashimoto, H.,Horton, J.R.,Zhang, X.,Cheng, X.
UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Epigenetics, 4:8-14, 2009
Cited by
PubMed: 19077538
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.41 Å)
Structure validation

217705

数据于2024-03-27公开中

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