3FDE
Mouse UHRF1 SRA domain bound with hemi-methylated CpG DNA, crystal structure in space group C222(1) at 1.4 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | E3 ubiquitin-protein ligase UHRF1 | polymer | 212 | 23915.7 | 2 | UniProt (Q8VDF2) Pfam (PF02182) | Mus musculus | Ubiquitin-like PHD and RING finger domain-containing protein 1, Ubiquitin-like-containing PHD and RING finger domains protein 1, Nuclear zinc finger protein Np95, Nuclear protein 95 |
| 2 | C, E (D, C) | 5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3' | polymer | 12 | 3637.4 | 2 | |||
| 3 | D, F (E, F) | 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3' | polymer | 12 | 3703.4 | 2 | |||
| 4 | BA, CA, DA, FA, G... (D, E, C, A, F...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 22 | Chemie (EDO) | |||
| 5 | EA, O, OA, W (E, A, F, B) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 6 | AA, GA, HA, IA, P... (B, C, A) | UNKNOWN LIGAND | non-polymer | 9 | Chemie (UNL) | ||||
| 7 | PA, QA, RA, SA, TA... (A, B, D, E, C...) | water | water | 18.0 | 680 | Chemie (HOH) |
Sequence modifications
A, B: 419 - 628 (UniProt: Q8VDF2)
| PDB | External Database | Details |
|---|---|---|
| His 417 | - | expression tag |
| Met 418 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 62513.0 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 1457.5 | |
| All* | Total formula weight | 63970.5 |
