3F8A

Crystal Structure of the R132K:R111L:L121E:R59W Mutant of Cellular Retinoic Acid-Binding Protein Type II Complexed with C15-aldehyde (a retinal analog) at 1.95 Angstrom resolution.

Summary for 3F8A

• Entry DOI: 10.2210/pdb3f8a/pdb
• Related: 3CR6 3F9D 3FA6 3FA7 3FA8 3FA9
• Descriptor: Cellular retinoic acid-binding protein 2, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene, ... (4 entities in total)
• Functional Keywords: crabpii, retinal, protonated schiff base, c15-aldehyde, retinoic acid, retinoid, nucleus, retinol-binding, transport, vitamin a, transport protein
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: P29373
• Total number of polymer chains: 1
• Total formula weight: 16041.41

Authors

Jia, X.,Geiger, J.H. (deposition date: 2008-11-12, release date: 2009-11-10, Last modification date: 2023-09-06)

• Primary citation: Lee, K.S.,Berbasova, T.,Vasileiou, C.,Jia, X.,Wang, W.,Choi, Y.,Nossoni, F.,Geiger, J.H.,Borhan, B.; Probing Wavelength Regulation with an Engineered Rhodopsin Mimic and a C15-Retinal Analogue; Chempluschem, 77:273-276, 2012

Experimental method

X-RAY DIFFRACTION (1.95 Å)