3CR6
Crystal Structure of the R132K:R111L:A32E Mutant of Cellular Retinoic Acid Binding Protein Type II Complexed with C15-aldehyde (a retinal analog) at 1.22 Angstrom resolution.
Summary for 3CR6
Entry DOI | 10.2210/pdb3cr6/pdb |
Descriptor | Cellular retinoic acid-binding protein 2, 1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene (3 entities in total) |
Functional Keywords | crabpii, retinal, schiff base, protonated schiff base, psb, c15-aldehyde, retinoic acid, retinoid, nucleus, retinol-binding, transport, vitamin a, transport protein |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P29373 |
Total number of polymer chains | 1 |
Total formula weight | 15772.14 |
Authors | Jia, X.,Geiger, J.H. (deposition date: 2008-04-04, release date: 2009-03-17, Last modification date: 2024-11-13) |
Primary citation | Jia, X.,Lee, K.S.,Vasileiou, C.,Borhan, B.,Geiger, J.H. Two distinctive orientations of binding determined by a single mutation in the CRABPII mutant-C15-aldehyde complexes To be Published, |
Experimental method | X-RAY DIFFRACTION (1.22 Å) |
Structure validation
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