3F7R

First pair of Fibronectin type III domains and part of the connecting segment of the integrin beta4

Summary for 3F7R

Entry DOI	10.2210/pdb3f7r/pdb
Related	1QG3 3F7P 3F7Q
Descriptor	Integrin beta-4, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywords	integrin, hemidesmosome, cell adhesion, carcinoma, epidermolysis bullosa, alternative splicing, disease mutation, glycoprotein, membrane, phosphoprotein, polymorphism, receptor, transmembrane
Biological source	Homo sapiens (human)
Cellular location	Membrane; Single-pass type I membrane protein: P16144
Total number of polymer chains	1
Total formula weight	27905.63
Authors	de Pereda, J.M. (deposition date: 2008-11-10, release date: 2009-03-10, Last modification date: 2023-11-01)
Primary citation	de Pereda, J.M.,Lillo, M.P.,Sonnenberg, A. Structural basis of the interaction between integrin alpha6beta4 and plectin at the hemidesmosomes Embo J., 28:1180-1190, 2009 Cited by PubMed: 19242489 DOI: 10.1038/emboj.2009.48 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.036 Å)

Structure validation