3F7R

First pair of Fibronectin type III domains and part of the connecting segment of the integrin beta4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007160	biological_process	cell-matrix adhesion
A	0007229	biological_process	integrin-mediated signaling pathway
A	0008305	cellular_component	integrin complex
A	0031581	biological_process	hemidesmosome assembly
A	0048870	biological_process	cell motility

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 201

Chain	Residue
A	HOH127
A	GLY1139
A	SER1140
A	ARG1141
A	LYS1142

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG A 301

Chain	Residue
A	ASN1185
A	TYR1187

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PEG A 302

Chain	Residue
A	HOH128
A	ASP1175
A	TYR1199
A	GLU1204
A	MET1270
A	LYS1299
A	GLU1309
A	ILE1328
A	HOH25
A	HOH45

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 303

Chain	Residue
A	HOH132
A	LYS1177
A	GLU1254
A	LYS1299
A	TRP1306

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	89
Details	Domain: {"description":"Fibronectin type-III 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	99
Details	Domain: {"description":"Fibronectin type-III 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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